Peeling Nails or Nails Falling Off? Onychomadesis after Hand, Foot, and Mouth in Kids 388

First, my 6 year old lost a finger nail. I thought maybe he squished it or snagged it on something and just said nothing because he’s a tough boy. The next day, the nurse called me to ask if I knew about his finger. I thought it was the same one and said yes, but when he got home, I found he was missing yet another nail. The whole thing was just gone.

I assumed maybe he had brittle nails for some reason—iron deficiency maybe—and put him on a multi-vitamin. Fast forward about 3 days, my 2 year old’s entire big toe nail just falls off. No blood, no pain, it was just gone, like his nail peeled off. I looked at all three kids, and they all had nails peeling off! Alright, now I was freaked out. What the heck was happening? Was it a fungus? Why were my kid’s nails falling off?
Peeling Nails Nails Falling Off shedding nails Onychomadesis hand foot and mouth
Well, now we have to go back in time, to about a month ago, when my entire household had a bad case of hand, foot, and mouth. As it turns out, peeling nails, nail shedding, or nail loss, also known as Onychomadesis, is a little known complication of hand, foot, and mouth typically presenting about 3 to 4 weeks after infection, but may occur anywhere from 1 to 10 weeks after.

What is Onychomadesis, and why does it happen?

Onychomadesis is a fancy medical word for the occurrence of peeling nails which may break or fall off completely shedding at the nail bed. You may notice the nail turns white before falling off, and there may or may not be a new nail beginning to grow in below it.

Onychomadesis is caused by a temporary stop or slowing in nail growth. In this case, the hand, foot, and mouth virus itself interrupts growth. So, as the nail grows up and out, there is a gap, so to speak, in the nail bed, which causes the nail above it to fall off. In minor cases, only slight indention or lines on the nails may be seen.

As hand, foot, and mouth primarily attacks the feet and hands, it makes sense that it may also affect the nail bed—this just certainly was not something I had ever heard of, and it didn’t happen the first time my kids had hand, foot, and mouth. It’s suggested that only certain strains of hand, foot, and mouth cause peeling nails, shedding, or nails falling off.

What do I do if my kid has peeling nails or nails falling off?

Yeah, there’s some horror movie gross-out with this one, seriously, it is disturbing, but all my kids communicate well, and they all said that it didn’t hurt.

In fact, when I removed the remainder of one nail falling off, my 2 year old didn’t even flinch. So, while peeling nails shedding off may look painful and very yucky, it likely isn’t causing your child pain.

Your best bet is to simply keep your child’s hands clean and leave them alone. New nails will grow in and rather quickly actually. The condition is not permanent, so if it keeps happening, you should definitely speak with your pediatrician. There are other causes of nail peeling, nails falling off, or nail shedding, but honestly, they are uncommon. Even fungal infections tend to only damage nails, not make them just sort of fall off.

Anyway, I will say this whole experience was rather educational. The wonderful thing about kids—and even crappy situations like lost nails in kids—is that you learn something new everyday.

This page has received so many comments, I was inspired to learn more about nails actually, specifically whether or not research supported any ways to help nails grow back faster which you can read about here.

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Iv been searching the web to find out why my sons nails were falling off at first I thought he had banged them in a door but after looking at all his nails 6/10 were all cracked and parts missing so thank gif I came across this he also had hfm just over 5 weeks ago now gonna still get him checked out just incase but it’s reassuring to know we’re not the only ones that have gone through it x


Thanks yes this makes sense 🙂 we had a bout of hfmd a month ago and presenting with the nail issues now!


My son has recently started to lose a few of his fingernails, I will be booking into the doctors first thing tomorrow. I do however feel relieved after reading this article as my son also had hand foot and month disease about 3/4 weeks ago so I’m assuming this will be the cause but still will get him checked out just in case. My other son also had hand foot and month so I’m now just wondering if he will lose his nails or if he’s been lucky… suppose time will tell. Thank you for posting your article as I… Read more »